Selected Publications

Quantitative mining of compositional heterogeneity in cryo-EM datasets of ribosome assembly intermediates.
Rabuck-Gibbons JN, Lyumkis D, Williamson JR.
Structure (2022). Apr 7;30(4):498-509.e4. doi: 10.1016/j.str.2021.12.005.
PMID: 34990602

SrmB rescues trapped ribosome assembly intermediates.
Rabuck-Gibbons JN, Popova AM, Greene EM, Cervantes CF, Lyumkis D, Williamson JR.
Journal of Molecular Biology (2020). Feb 14;432(4):978-990. doi: 10.1016/j.jmb.2019.12.013.
PMID: 31877323

A universal trade-off between growth and lag in fluctuating environments.
Basan M, Honda T, Christodoulou D, Hörl M, Chang YF, Leoncini E, Mukherjee A, Okano H, Taylor BR, Silverman JM, Sanchez C, Williamson JR, Paulsson J, Hwa T, Sauer U.
Nature (2020). Aug;584(7821):470-474. doi: 10.1038/s41586-020-2505-4.
PMID: 32669712

Transient Protein-RNA Interactions Guide Nascent Ribosomal RNA Folding.
Duss O, Stepanyuk GA, Puglisi JD, Williamson JR.
Cell (2019). Nov 27;179(6):1357-1369.e16. doi: 10.1016/j.cell.2019.10.035.
PMID: 31761533

Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts.
Duss O, Stepanyuk GA, Grot A, O’Leary SE, Puglisi JD, Williamson JR.
Nature Communications (2018). Nov 30;9(1):5087. doi: 10.1038/s41467-018-07423-3.
PMID: 30504830

A global resource allocation strategy governs growth transition kinetics of Escherichia coli.
Erickson DW, Schink SJ, Patsalo V, Williamson JR, Gerland U, Hwa T.
Nature (2017). Nov 2;551(7678):119-123. doi: 10.1038/nature24299.
PMID: 29072300

Addressing preferred specimen orientation in single-particle cryo-EM through tilting.
Tan YZ, Baldwin PR, Davis JH, Williamson JR, Potter CS, Carragher B, Lyumkis D.
Nat Methods (2017). Aug;14(8):793-796. doi: 10.1038/nmeth.4347.2017.
PMID: 28671674

Modular Assembly of the Bacterial Large Ribosomal Subunit.
Davis JH, Tan YZ, Carragher B, Potter CS, Lyumkis D, Williamson JR.
Cell (2016). Dec 1;167(6):1610-1622.e15. doi: 10.1016/j.cell.2016.11.020.
PMID: 27912064

Overflow metabolism in Escherichia coli results from efficient proteome allocation.
Basan M, Hui S, Okano H, Zhang Z, Shen Y, Williamson JR, Hwa T.
Nature (2015). Dec 3;528(7580):99-104. doi: 10.1038/nature15765.
PMID: 26632588

Toward a Whole-Cell Model of Ribosome Biogenesis: Kinetic Modeling of SSU Assembly.
Earnest TM, Lai J, Chen K, Hallock MJ, Williamson JR, Luthey-Schulten Z.
Biophys J (2015). Sep 15;109(6):1117-35. doi: 10.1016/j.bpj.2015.07.030.
PMID: 26333594

Really exasperating viral protein from HIV.
Williamson JR.
Elife (2015). Jan 9;4. doi: 10.7554/eLife.05169.
PMID: 25574642

A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli.
Sashital DG, Greeman CA, Lyumkis D, Potter CS, Carragher B, Williamson JR.
Elife (2014). Oct 14;3. doi: 10.7554/eLife.04491.
PMID: 25313868

Discovery of a small molecule that inhibits bacterial ribosome biogenesis.
Stokes JM, Davis JH, Mangat CS, Williamson JR, Brown ED.
Elife (2014). Sep 18;3:e03574. doi: 10.7554/eLife.03574.
PMID: 25233066

A new system for naming ribosomal proteins.
Ban N, Beckmann R, Cate JH, Dinman JD, Dragon F, Ellis SR, Lafontaine DL,…, Williamson JR, Wilson D, Yonath A, Yusupov M.
Curr Opin Struct Biol (2014). Feb;24:165-9. doi: 10.1016/
PMID: 24524803

Quantitative analysis of rRNA modifications using stable isotope labeling and mass spectrometry.
Popova AM, Williamson JR.
J Am Chem Soc (2014). Feb 5;136(5):2058-69. doi: 10.1021/ja412084b.
PMID: 24422502

Functional domains of the 50S subunit mature late in the assembly process.
Jomaa A, Jain N, Davis JH, Williamson JR, Britton RA, Ortega J.
Nucleic Acids Res (2014). Mar;42(5):3419-35. doi: 10.1093/nar/gkt1295.
PMID: 24335279